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Used 2021 Mercedes-Benz E 350 for Sale in

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San Diego, CA
Value: 75 miles
Min: 75 milesMax: 75 miles
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Find a Used 2021 Mercedes-Benz E 350 in San Diego, CA

TrueCar has 10 used 2021 Mercedes-Benz E 350 models for sale in San Diego, CA, including a 2021 Mercedes-Benz E 350 Sedan RWD and a 2021 Mercedes-Benz E 350 Sedan 4MATIC. Prices for a used 2021 Mercedes-Benz E 350 in San Diego, CA currently range from $21,326 to $44,998, with vehicle mileage ranging from 4,849 to 104,890.

Nationwide Mercedes-Benz E-Class Listings by Year

VehiclePrice FromCertified Pre-OwnedUnder 100k MilesAccident FreeTotal Available
2025 Mercedes-Benz E-Class$52,88869 listings138 listings136 listings138 listings
2024 Mercedes-Benz E-Class$45,99525 listings49 listings46 listings49 listings
2023 Mercedes-Benz E-Class$34,99529 listings57 listings55 listings57 listings
2022 Mercedes-Benz E-Class$23,69551 listings139 listings112 listings139 listings
2021 Mercedes-Benz E-Class$21,32623 listings117 listings82 listings118 listings
2020 Mercedes-Benz E-Class$17,9006 listings80 listings53 listings81 listings
2016 Mercedes-Benz E-Class$9,4950 listings70 listings55 listings109 listings
2015 Mercedes-Benz E-Class$9,5930 listings38 listings36 listings53 listings
2014 Mercedes-Benz E-Class$6,9850 listings155 listings159 listings259 listings
2013 Mercedes-Benz E-Class$6,8970 listings36 listings52 listings74 listings

2021 Mercedes-Benz E-Class Owner Reviews

9th Generation Mercedes-Benz E-Class

2017 - 2023
Overall Rating
4.9
10 out of 10
Based on 26 Ratings
Performance
4.9
Comfort
4.9
Fuel Efficiency
4.6
Safety Technology
4.9
Features
4.9
All reviews
5.010 out of 10
Performance
4.0
Comfort
5.0
Fuel Efficiency
4.0
Safety Technology
5.0
Features
5.0
Performance
4.0
Comfort
5.0
Fuel Efficiency
4.0
Safety Technology
5.0
Features
5.0
pros
Best wagon on the market, quiet, comfortable, performance, features, can't imagine a better daily driver.
cons
If you want the best wagon on the market, you have to pay for the best wagon on the market. At least they hold their value well.
Submitted by Anonymous Author on --- --- ----|2021 Mercedes-Benz E-Class E 450 Wagon All-Terrain 4MATIC
5.010 out of 10
Performance
5.0
Comfort
5.0
Fuel Efficiency
5.0
Safety Technology
5.0
Features
5.0
pros
I really like the adjustability of the seats. They are very comfortable while cruising, and have active air bags in the side bolsters to keep the driver secure while taking turns at speed. Optioned with the acoustic film on the glass, the exhaust system isn’t shouty like most fast ICE cars, allowing me to use it in any situation without issues.
cons
The initial time it took me to understand and use the infotainment properly was considerable. Although it is complicated, now that I know how to navigate the buttons and screens, it is fine.
Submitted by Jac M on --- --- ----|2021 Mercedes-Benz E-Class AMG E 63 S Wagon 4MATIC+|Purchased on --- --- ----
5.010 out of 10
Performance
5.0
Comfort
4.0
Fuel Efficiency
5.0
Safety Technology
4.0
Features
4.0
pros
The look and the performance of the vehicle.
cons
The foot trunk opener is very different to use.
Submitted by Gail R on --- --- ----|2021 Mercedes-Benz E-Class E 450 Coupe 4MATIC|Purchased on --- --- ----