Skip to content

Used 2021 Mercedes-Benz E 350 for Sale in

Buy Online
Buy your next car 100% online through TrueCar+ with transparent pricing, no hidden fees and home delivery
Popular filters
Vehicle Condition
Brand
Key Biscayne, FL
Value: 75 miles
Min: 75 milesMax: 75 miles
Include non-local listings
Price
Price drop
Condition

Vehicle history data is provided by Experian AutoCheck. Use of this data is subject to the AutoCheck Terms & Conditions.

POPULAR exterior colors
POPULAR interior colors
Body style
Features
Fuel type
Transmission
Drivetrain
Reset all
19 Listings
Clear all

Find a Used 2021 Mercedes-Benz E 350 in Key Biscayne, FL

TrueCar has 19 used 2021 Mercedes-Benz E 350 models for sale in Key Biscayne, FL, including a 2021 Mercedes-Benz E 350 Sedan RWD and a 2021 Mercedes-Benz E 350 Sedan 4MATIC. Prices for a used 2021 Mercedes-Benz E 350 in Key Biscayne, FL currently range from $21,326 to $44,998, with vehicle mileage ranging from 4,849 to 104,980.

Nationwide Mercedes-Benz E-Class Listings by Year

VehiclePrice FromCertified Pre-OwnedUnder 100k MilesAccident FreeTotal Available
2025 Mercedes-Benz E-Class$52,88669 listings142 listings140 listings142 listings
2024 Mercedes-Benz E-Class$45,99524 listings52 listings48 listings52 listings
2023 Mercedes-Benz E-Class$34,99529 listings60 listings58 listings60 listings
2022 Mercedes-Benz E-Class$23,69550 listings139 listings113 listings139 listings
2021 Mercedes-Benz E-Class$21,32629 listings119 listings84 listings120 listings
2020 Mercedes-Benz E-Class$17,9009 listings80 listings52 listings80 listings
2016 Mercedes-Benz E-Class$8,1490 listings67 listings51 listings106 listings
2015 Mercedes-Benz E-Class$9,5930 listings37 listings37 listings52 listings
2014 Mercedes-Benz E-Class$6,9851 listing149 listings153 listings251 listings
2013 Mercedes-Benz E-Class$6,8970 listings35 listings50 listings72 listings

2021 Mercedes-Benz E-Class Owner Reviews

9th Generation Mercedes-Benz E-Class

2017 - 2023
Overall Rating
4.9
10 out of 10
Based on 26 Ratings
Performance
4.9
Comfort
4.9
Fuel Efficiency
4.6
Safety Technology
4.9
Features
4.9
All reviews
5.010 out of 10
Performance
4.0
Comfort
5.0
Fuel Efficiency
4.0
Safety Technology
5.0
Features
5.0
Performance
4.0
Comfort
5.0
Fuel Efficiency
4.0
Safety Technology
5.0
Features
5.0
pros
Best wagon on the market, quiet, comfortable, performance, features, can't imagine a better daily driver.
cons
If you want the best wagon on the market, you have to pay for the best wagon on the market. At least they hold their value well.
Submitted by Anonymous Author on --- --- ----|2021 Mercedes-Benz E-Class E 450 Wagon All-Terrain 4MATIC
5.010 out of 10
Performance
5.0
Comfort
5.0
Fuel Efficiency
5.0
Safety Technology
5.0
Features
5.0
pros
I really like the adjustability of the seats. They are very comfortable while cruising, and have active air bags in the side bolsters to keep the driver secure while taking turns at speed. Optioned with the acoustic film on the glass, the exhaust system isn’t shouty like most fast ICE cars, allowing me to use it in any situation without issues.
cons
The initial time it took me to understand and use the infotainment properly was considerable. Although it is complicated, now that I know how to navigate the buttons and screens, it is fine.
Submitted by Jac M on --- --- ----|2021 Mercedes-Benz E-Class AMG E 63 S Wagon 4MATIC+|Purchased on --- --- ----
5.010 out of 10
Performance
5.0
Comfort
4.0
Fuel Efficiency
5.0
Safety Technology
4.0
Features
4.0
pros
The look and the performance of the vehicle.
cons
The foot trunk opener is very different to use.
Submitted by Gail R on --- --- ----|2021 Mercedes-Benz E-Class E 450 Coupe 4MATIC|Purchased on --- --- ----